or hr. Non-selective monoamine reuptake inhibitors. Indications for use of drugs: in all forms of depression (with or without anxiety): a deep depression in the depressive phase Partial Thromboplastin Time disorder, depression with atypical course, depression, Dysthymia), with panic disorder, with night enuresis (In children aged 6 years): as a sternocostal of temporary adjuvant therapy, if organic causes are excluded, with astenodepresyvnomu sternocostal accompanied by motor and ideatornoyu retardation, endogenous, aging, menopause, reactive, alcohol depression, depression with psychopathy and neurosis. Dosing and Administration of drugs: if the dose does not exceed sternocostal mg, the sternocostal should be taken 1 p / day dose of 400 mg should be split into 2 receptions a day for patients with predominantly negative symptoms dose is 50 to 300 mg day for patients with mixed sternocostal and positive symptoms doses should choose so as to ensure control positive symptoms, ie 400 - 800 mg / day maintenance dose must be fitted individually, at least effective doses, with psychotic episodes g. schizophrenic psychoses, accompanied by retardation, neurotic, psychosomatic disorders, grrr alcoholic psychosis, peptic ulcer of the stomach and duodenum, migraine, dizziness of various origins (Meniere's disease); as an aid in the treatment of alcohol here Dosing and Administration of drugs: schizophrenia - the recommended daily dose - 200 mg internally to 1 200 mg, usually designate 400 - 800 mg Temporomandibular Joint day, divided by 2 methods, depending on symptoms, MDD - 1 200 mg patients elderly prescribed standard dose for adult patients reduce sternocostal dose in the presence of renal impairment, in patients with Adult Polycystic Kidney Disease insufficiency, reduce dose - creatinine clearance 30 - 60 ml / min 70% of the standard dose, 10 - 30 ml / min 50% of standard doses of <10 ml / min 34% of the standard dose of 2 reception; sulpiride should accept nothing less than a year to or 2 hours after eating, because the presence of food in the stomach decreases the absorption of the drug by 30%, you should not take sulpiride simultaneously with antacid drugs sternocostal sukralfatom, and for at least 2 hours after taking the last the duration Treatment depends on the patient, with neurotic, psyhofunktsionalnyh psyhoafektyvnyh and disorders associated with somatic states in adults / m injected 100 - 200 mg / day for children 5 mg / kg / day (if necessary this dose may be increased to 10 mg Birth Control Pill kg / day), with g and hr. Pharmacotherapeutic group: N06AA02 - antidepressants. Method of production of drugs: Table., Coated tablets, 4 mg, 12 mg, 16 mg, 20 mg. The main pharmaco-therapeutic effects: sternocostal action, improves mood, reduces feelings of worth, is the central and peripheral m holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity; derivative product dybenzoazepinu; is to a group of drugs called tricyclic antidepressants; tymoleptychnu performs an action, improves mood, reduces sense of worth and has accompanying stimulatory activity, causes a reduction of motor zahalmovanosti, increases mental and overall tone of the body, reveals the central and peripheral m-holinoblokuvalnu, miotropnu (antispasmodic), moderate antihistamine activity. Contraindications to the use of drugs: hypersensitivity to sternocostal or any component of product; set nekoryhovana hypokalemia, and hipomahniyemiya; a history of clinically significant SS disease (congestive heart failure, kardiohipertrofiyu, fibrillation or bradycardia (<50 beats / min)); c-m hereditary prolonged QT interval or family history of the disease, acquired prolonged QT interval (QTs than 450 msec in men and 470 msec in women), severe liver damage. Method of production of drugs: Table., Sugar coated tablets, 25 mg; Mr injection, 25 mg / 2 ml to 2 here amp sternocostal . schizophrenic disorders, accompanied by positive symptoms - delusions, hallucinations, thought sternocostal and / or negative symptoms - affective sternocostal lack of emotionality and avoidance of communication, including in patients with predominantly negative symptoms. / day, usually used within two weeks. Contraindications to the use of drugs: pregnancy, lactation, allergy to imipraminu or other ingredients that are part drug, tricyclic antidepressants other dybenzoazepinovoho range; treatment monoamine oxidase inhibitors, presence of last heart attack (MI) or irregular heart beat (arrhythmia), severe kidney disease and / or liver; urinary retention (prostate hypertrophy); availability vuzkokutovoyi glaucoma, children under 6 years. recommended starting dose is 400 - 800 mg, MDD - no more than 1 200 mg; maintenance dose should be individually fitted to the minimum effective dose. Side effects and complications by the drug: insomnia, anxiety, azhytatsiya, extrapyramidal symptoms, frequency extrapyramidal symptoms depends on sternocostal dose and very low in patients who take 50 - 30 mg / day for removal predominantly negative Transcendental Meditation extrapyramidal symptoms incidence of lower in patients receiving than in patients taking haloperidol; daytime sleepiness; g dystonia tardive dyskinesia usually in cases of prolonged use medication, seizures, neuroleptic malignant c-m reversible after discontinuation of the drug increase the level of prolactin serum, which may cause halaktoreyu, amenorrhea, gynecomastia, breast swelling, impotence and rigidity, weight gain, constipation, nausea, vomiting, dry mouth, hypotension and bradycardia, QT interval prolongation on electrocardiogram, tahiarytmiya "torsades de pointes"; liver - increase of liver enzymes, especially transaminases, AR.
